PRDM5 Antibody (YA4517)(PBS only),MedChemexpress,HY-P84820A

PRDM5 Antibody (YA4517) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRDM5.

Host

Mouse

Reactivity

Human,Mouse

Application

WB,ICC/IF,FC,ELISA

Conjugate

Non-conjugated

Platform ID

BAB828230979

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePRDM5 Antibody (YA4517)(PBS only)
Cat. No.HY-P84820A
Accession NumberQ9NQX1
Gene ID (Entrez)11107
HostMouse
IsotypeIgG1
ReactivityHuman,Mouse
ConjugationNon-conjugated
ApplicationWB,ICC/IF,FC,ELISA
Working DilutionsWB: 1:500-1:2000; ICC/IF: 1:100-1:500; FC: 1:200-1:400; ELISA: 1:10000
Clone NumberYA4517
Molecular WeightPredicted band size: 73 kDa; Observed band size: 70-75 kDa
ImmunogenPurified recombinant fragment of human PRDM5 (AA: 1-100) expressed in E. Coli.
Purityaffinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, pH 7.4.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

PRDM5 is a sequence-specific DNA-binding transcription factor that represses transcription, in part by recruiting the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. It regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes and may modulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens (e.g., COL4A1 and COL11A1), connective tissue components (e.g., HAPLN1), and molecules regulating cell migration and adhesion (e.g., EDIL3 and TGFB2). Additionally, PRDM5 may induce G2/M arrest and apoptosis in cancer cells.

Synonyms

BCS2; PFM2

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.