PRNP Recombinant Antibody,Bioss,bsm-52505r-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB165752108

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePRNP Recombinant Antibody
Cat. No.bsm-52505r-100ul
Accession NumberP04156
Gene ID (Entrez)5621
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IHC-P:IHC-P1:50-200 | IHC-F:IHC-F1:50-200 | IF(IHC-P):IFIHC-P1:50-200 | IF(ICC):IFICC1:50-200
ClonalityRecombinant
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageStore at -20°C for 12 months.

Scientific Background

The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

Synonyms

Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.