PSA(Pa3) Monoclonal Antibody,Bioss,bsm-1625m-100ul

Host

Mouse

Reactivity

Human

Application

WB, ELISA, IHC-P, IF(IHC-P)

Conjugate

Unconjugated

Platform ID

BAB193250167

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NamePSA(Pa3) Monoclonal Antibody
Cat. No.bsm-1625m-100ul
Gene ID (Entrez)354
HostMouse
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, ELISA, IHC-P, IF(IHC-P)
Working DilutionsWB:1:300-5000 | ELISA:1:500-1000 | IHC-P:1:200-400 | IF(IHC-P):1:50-200
ClonalityMonoclonal
Concentration1ug/ul
PurityPurified by Protein G.
Formulation0.01M PBS (pH7.4) with 0.02% Proclin300.
StorageStore at -20°C for 12 months.

Scientific Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Synonyms

Prostate specic antigen; Gamma seminoprotein; hK3; Kallikrein 3; Kallikrein related peptidase 3; KLK 3; KLK2A1; KLK3; P 30 antigen; P30 antigen; Prostate Specic Antigen; PSA; Semenogelase; Seminin.

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