PSA antibody [A67-B/E3] (Biotin),Genetex,GTX80247

Host

Mouse

Reactivity

Human

Application

WB IHC-P ELISA

Conjugate

Biotin The reagent is free of unconjugated biotin.

Platform ID

BAB060571585

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamePSA antibody [A67-B/E3] (Biotin)
Cat. No.GTX80247
Gene ID (Entrez)354
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationBiotin The reagent is free of unconjugated biotin.
ApplicationWB IHC-P ELISA
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetKLK3
Immunogen30 KDa protein fraction prepared from human seminal plasma
PurityPurified IgG
Appearance/FormLiquid
FormulationPBS,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Synonyms

APS , KLK2A1 , KLK3 , PSA , hK3 , kallikrein related peptidase 3 , Prostate specific antigen

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