PTBP2 Antibody (YA2902),MedChemexpress,HY-P83157

PTBP2 Antibody (YA2902) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTBP2.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF

Conjugate

Non-conjugated

Platform ID

BAB330691062

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
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Product Specifications
Scientific Background
Synonyms

Specifications

NamePTBP2 Antibody (YA2902)
Cat. No.HY-P83157
Accession NumberQ9UKA9
Gene ID (Entrez)58155
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF
Working DilutionsWB: 1:1000-1:2000; IHC-P: 1:100-1:200; ICC/IF: 1:50-1:200
ClonalityRecombinant,Monoclonal
Clone NumberYA2902
Molecular WeightPredicted band size: 57 kDa; Observed band size: 57 kDa
ImmunogenA synthesized peptide derived from human PTBP2 aa1-42.
PurityAffinity Chromatography
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

PTBP2 is an RNA-binding protein that binds to intronic polypyrimidine tracts and mediates negative regulation of exon splicing. It may antagonize, in a tissue-specific manner, the ability of NOVA1 to activate exon selection. In addition to its role in pre-mRNA splicing, PTBP2 also functions in the regulation of translation; by similar: its affinity for RNA is reduced.

Synonyms

brPTB; MIBP; nPTB; Polypyrimidine tract binding protein 2; PTB like protein; PTBP 2Ptbp2; Splicing regulator

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