PTCH1 antibody [5c7],Genetex,GTX83771
Host
Mouse
Reactivity
Human
Application
WB ICC/IF IHC-P
Conjugate
Unconjugated
Platform ID
BAB819242421
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NamePTCH1 antibody [5c7]
Cat. No.GTX83771
Gene ID (Entrez)5727
HostMouse
IsotypeIgG2b
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityMonoclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPTCH1
ImmunogenHuman recombinant protein fragment corresponding to amino acids 122-436 of human PTCH1 (NP_000255) produced in E.coli.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Synonyms
patched 1 , BCNS , NBCCS , PTC , PTC1 , PTCH
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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