PTPD1 antibody,Genetex,GTX03798

Host

Rabbit

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB723710827

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePTPD1 antibody
Cat. No.GTX03798
Gene ID (Entrez)11099
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetPTPN21
ImmunogenThis PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.
PurityPurified by saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS,0.09% sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]

Synonyms

protein tyrosine phosphatase non-receptor type 21 , PTPD1 , PTPRL10

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.