Pacific Blue anti-human CD235a Glycophorin A Antibody anti-CD235a - HI264,BioLegend,349107

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB839398948

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePacific Blue anti-human CD235a Glycophorin A Antibody anti-CD235a - HI264
Cat. No.349107
HostMouse
RRIDAB_11219199 (BioLegend Cat. No. 349107)AB_11218988 (BioLegend Cat. No. 349108)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHI264
TargetCD235a
PurityThe antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD235a (Glycophorin A) is member of the glycophorin A family. It is a type I sialoglycoprotein with a molecular weight of 10 kD, present in the cell membrane as a homodimer. Glycophorin A is expressed by erythroid precursors and erythrocytes.  It carries the antigen determinants for the MNS blood groups and has been proposed to be an inhibitor of hemagglutination and hemolysis. Glycophorin A binds siglec 5, the erythrocyte binding antigen (EBA-175) ofP. falciparumand some viruses, including influenza virus and hepatitis A virus.

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