Pacific Blue anti-human CD335 NKp46 Antibody anti-CD335 - 9E2,BioLegend,331911
Clone 9E2 has been shown to block NK activation through NKp46.6
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB450440680
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePacific Blue anti-human CD335 NKp46 Antibody anti-CD335 - 9E2
Cat. No.331911
HostMouse
RRIDAB_2149281 (BioLegend Cat. No. 331911)AB_2149280 (BioLegend Cat. No. 331912)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number900
Concentration0.5 mg/ml
TargetCD335
ImmunogenNKp46-Fc fusion protein
PurityThe antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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