Pacific Blue anti-mouse CD21/CD35 CR2/CR1 Antibody anti-CD21/35 - 7E9,BioLegend,123414
Additional reported application (for relevant formats) include: spatial biology (IBEX)5,6.
Host
Rat
Reactivity
Mouse
Application
FC - Quality testedSB - Reported in the literature, not verified in house
Platform ID
BAB822229722
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePacific Blue anti-mouse CD21/CD35 CR2/CR1 Antibody anti-CD21/35 - 7E9
Cat. No.123414
HostRat
RRIDAB_2085159 (BioLegend Cat. No. 123413)AB_2085158 (BioLegend Cat. No. 123414)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality testedSB - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone Number7000000000
Concentration0.5 mg/ml
TargetCD21/CD35
ImmunogenCD35/CFA
PurityThe antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD21, also known as CR2 (complement receptor 2) and C3d receptor, binds C3d and iC3b. It is also a receptor of Epstein-Barr virus. CD35, also known as CR1, binds C3b, iC3b, C4b, and iC4b. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81 and is involved in signal transduction.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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