Pacific Blue anti-mouse Ki-67 Antibody anti-Ki-67 - 16A8,BioLegend,652421

Host

Rat

Reactivity

Mouse

Application

ICFC -Quality tested

Platform ID

BAB668258606

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePacific Blue anti-mouse Ki-67 Antibody anti-Ki-67 - 16A8
Cat. No.652421
HostRat
RRIDAB_2564489 (BioLegend Cat. No. 652421)AB_2564490 (BioLegend Cat. No. 652422)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationICFC -Quality tested
ClonalityMonoclonal
Clone Number16A8
Concentration0.5 mg/ml
TargetKi-67
ImmunogenE. coliexpressed partial mouse Ki-67 recombinant protein, 1816-2163 aa.
PurityThe antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase, while in G0 phase the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.

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