Pan Lactic acid-Lysine Rabbit pAb- ABclonal,ABclonal,A18831
Reactivity
Human, Mouse, Rat, Other (Wide Range)
Application
WB, ELISA
Platform ID
BAB714824979
ABclonal
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Product Specifications
Scientific Background
Specifications
NamePan Lactic acid-Lysine Rabbit pAb- ABclonal
Cat. No.A18831
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat, Other (Wide Range)
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages. In M1 macrophages, lactic acid is derived from incompletely oxidized glucose and then produces lactyl-CoA, which is transferred via acetyltransferase p300 to the lysine tail of the histone. This modification is abundant in gene promoter regions that lack acetylation and are associated with gene expression activation.
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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