Papillary renal cell carcinoma Rabbit pAb- ABclonal,ABclonal,A18781

Reactivity

Human

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB049120762

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NamePapillary renal cell carcinoma Rabbit pAb- ABclonal
Cat. No.A18781
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight66kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.

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