Pappalysin 2 antibody,Genetex,GTX85150

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB886121568

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePappalysin 2 antibody
Cat. No.GTX85150
Gene ID (Entrez)60676
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPAPPA2
ImmunogenPLAC3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3.The immunogen is located within amino acids 450 - 500 of PLAC3.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.

Synonyms

pappalysin 2 , PAPP-A2 , PAPP-E , PAPPE , PLAC3

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.