PerCP Anti-CD20 antibody [2H7],Abcam,AB114860

The mouse monoclonal antibody 2H7 recognizes CD20 (B1, Bp35), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on pre-B lymphocytes, resting and activated B cells (not plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes. Purified antibody is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.

Host

Mouse

Reactivity

Human, Primates

Application

Flow Cyt

Conjugate

PerCP

Platform ID

BAB369155807

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NamePerCP Anti-CD20 antibody [2H7]
Cat. No.AB114860
HostMouse
IsotypeIgG2b
ReactivityHuman, Primates
ConjugationPerCP
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number2H7
ImmunogenCell preparation containing MS4A1 protein. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed : 12920111, PubMed : 3925015, PubMed : 7684739). Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed : 12920111, PubMed : 18474602, PubMed : 7684739). See full target information MS4A1

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