PerCP/Cy5.5® Anti-IL3RA/CD123 antibody [6H6],Abcam,AB157332

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

PerCP/Cy5.5®

Platform ID

BAB619680555

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NamePerCP/Cy5.5® Anti-IL3RA/CD123 antibody [6H6]
Cat. No.AB157332
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationPerCP/Cy5.5®
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number6H6
ImmunogenCell preparation containing IL3RA protein. The exact immunogen used to generate this antibody is proprietary information.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed : 10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity). See full target information IL3RA

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