PerCP/Cyanine5.5 anti-Tubulin β 3 (TUBB3) Antibody, Tubulin β 3 (TUBB3), TUJ1,BioLegend,801216
Additional reported applications (for the relevant formats) include: flow cytometry4, immunofluorescence microscopy1-5,7, immunohistochemistry5,7, Western blotting8, and spatial biology (IBEX)9,10.This antibody is well characterized and highly reactive to neuron specific Class III ß-tubulin (ßIII). TUJ1 does not identify ß-tubulin found in glial cells. TUJ1 recognizes an epitope located within the last 15 C-terminal residues8.
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
ICFC - Quality tested
Platform ID
BAB471919101
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NamePerCP/Cyanine5.5 anti-Tubulin β 3 (TUBB3) Antibody, Tubulin β 3 (TUBB3), TUJ1
Cat. No.801216
HostMouse
RRIDAB_2876746 (BioLegend Cat. No. 801215)AB_2876746 (BioLegend Cat. No. 801216)
IsotypeMouse IgG2a, κ
ReactivityHuman, Mouse, Rat
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberTUJ1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetTubulin beta-3
ImmunogenThis antibody was raised against microtubules derived from rat brain.
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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