PerCP/Cyanine5.5 anti-human CD117 c-kit Antibody anti-CD117 - 104D2,BioLegend,313213
The 104D2 antibody does not block binding of c-Kit ligand. Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunofluorescence microscopy1, and spatial biology (IBEX)4,5.
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB849527877
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NamePerCP/Cyanine5.5 anti-human CD117 c-kit Antibody anti-CD117 - 104D2
Cat. No.313213
HostMouse
RRIDAB_893226 (BioLegend Cat. No. 313213)AB_2131443 (BioLegend Cat. No. 313214)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number104D2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD117
ImmunogenMOLM-1 megakaryocytic cell line
PurityThe antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.