PerCP/Cyanine5.5 anti-human CD30 Antibody anti-CD30 - BY88,BioLegend,333912

Additional reported application: in combination with IL-2 and PMA to induce T cell clone proliferation.

Host

Mouse

Reactivity

Human

Application

ICFC -Quality tested

Platform ID

BAB212709788

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human CD30 Antibody anti-CD30 - BY88
Cat. No.333912
HostMouse
RRIDAB_2566269 (BioLegend Cat. No. 333911)AB_2566270 (BioLegend Cat. No. 333912)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationICFC -Quality tested
ClonalityMonoclonal
Clone NumberBY88
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD30
ImmunogenRecombinant human CD30 boosted with THP-1 cell line
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD30, also known as Ki-1 antigen, lymphoid activation antigen CD30, and tumor necrosis factor receptor superfamily member 8 is a type I transmembrane receptor that contains four TNF receptor domains with an approximate molecular weight of 64 kD. CD30 is highly expressed on Hodgkins and Reed-Sternberg cells as well as activated, but not resting, T and B cells. CD30 has been shown to interact with a number of proteins including TRAF1, TRAF2, TRAF3, TRAF5, NPM-ALK, TRAF-interacting protein, and CD30 ligand (CD153). Signaling through CD30 is thought to limit the proliferative potential of autoreactive CD8 effector T cells and protect against autoimmunity.

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