PerCP/Cyanine5.5 anti-human CD304 Neuropilin-1 Antibody anti-CD304 - 12C2,BioLegend,354509

Host

Mouse

Reactivity

Human

Application

FC -Quality tested

Platform ID

BAB979765333

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human CD304 Neuropilin-1 Antibody anti-CD304 - 12C2
Cat. No.354509
HostMouse
RRIDAB_2561558 (BioLegend Cat. No. 354509)AB_2561559 (BioLegend Cat. No. 354510)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number12C2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD304
ImmunogenCD304-Fc Fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD304, also known as neuropilin-1, BDCA-4 and VEGF165R, is a 140 kD type I transmembrane protein. Its extracellular region contains 2 CUB, 2 FV/FVIII, and one MAM domain; a soluble isoform is produced by alternative mRNA splicing. CD304 is involved in angiogenesis, neural development, and tumor metastasis. It's expressed by plasmacytoid dendritic cells, thymocytes, neurons, endothelium, and a subset of TFHcells. CD304 is also expressed in several carcinomas, and a high expression of this molecule in prostate cancer correlates with a poor prognosis.

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