PerCP/Cyanine5.5 anti-human CD90 Thy1 Antibody anti-CD90 - 5E10,BioLegend,328117

Clone 5E10 recognizes an epitope on Thy-1 independent of its glycosylation, but is abolished under reducing conditions.4Additional reported (for the relevant formats) applications include: immunohistochemical staining of acetone-fixed frozen sections, immunoprecipitation1, and immunofluorescence3.

Host

Mouse

Reactivity

Human

Application

FC -Quality tested

Platform ID

BAB629388537

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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human CD90 Thy1 Antibody anti-CD90 - 5E10
Cat. No.328117
HostMouse
RRIDAB_961312 (BioLegend Cat. No. 328117)AB_2303335 (BioLegend Cat. No. 328118)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number50000000000
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD90
ImmunogenHEL cells
PurityThe antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.

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