PerCP/Cyanine5.5 anti-human CX3CR1,BioLegend,341614

Host

Rat

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB175727548

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human CX3CR1
Cat. No.341614
HostRat
RRIDAB_11218599 (BioLegend Cat. No. 341613)AB_11219203 (BioLegend Cat. No. 341614)
IsotypeRat IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number2A9-1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCX3CR1
ImmunogenCX3CR1-EGFP fusion protein
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also called GPR13 or V28. It is expressed on NK cells, T cell subset, monocytes/macrophages, dendritic cells, and some malignant epithelial cells. CX3CL1 (known also as fractalkine and neurotactin) is the ligand of CX3CR1. CX3CL1 is a unique transmembrane molecule with a CX3C-motif chemokine domain and a mucin-like stalk. CX3CL1 is expressed by activated-endothelial cells, neurons, and astrocytes. The interaction of CX3CR1 and its ligand mediatesfirm cell adhesion and migration.

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