PerCP/Cyanine5.5 anti-human EMR3 Recombinant Antibody, EMR3, QA20A59,BioLegend,366112

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB877691823

BioLegend

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Contact

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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human EMR3 Recombinant Antibody, EMR3, QA20A59
Cat. No.366112
HostMouse
RRIDAB_2936710 (BioLegend Cat. No. 366111)AB_2936710 (BioLegend Cat. No. 366112)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA20A59
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetEMR3
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

EMR3 is a member of the EGF-7 transmembrane (TM7) adhesion GPCR family. It is predominantly expressed on granulocytes, neutrophils, monocytes, and macrophages, and at lower levels on mature myeloid cells and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors.Studies suggest that the EMR3 molecule is upregulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. EMR3 may play a role in myeloid-myeloid interactions during immune and inflammatory responses.

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