PerCP/Cyanine5.5 anti-human TCR Cβ1 Antibody, TCR Cβ1, JOVI.1,BioLegend,383507

Clone JOVI.1 can interfere with the binding of clone IP26 on target cells.

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB803527439

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human TCR Cβ1 Antibody, TCR Cβ1, JOVI.1
Cat. No.383507
HostMouse
RRIDAB_2927883 (BioLegend Cat. No. 383507)AB_2927883 (BioLegend Cat. No. 383508)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberJOVI.1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetTCR Cbeta1
ImmunogenTransgenic mouse lymphocytes expressing human Vβ3-Cβ1 TCR
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

The T cell receptor beta chain constant region-1 (TCR Cβ1), also known as TRBC1, is a segment of the TCR beta chain that forms the constant region of the T cell receptor. The rearrangement of TCR genes during T cell development leads to the selection of one of two TCR beta constant regions – C1 or C2.  Detection of TRBC1 within a comprehensive T cell panel can be used as evidence of clonality akin to the use of kappa/lambda light chain detection in the diagnosis of plasma cell malignancies.

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