PerCP/Cyanine5.5 anti-human beta2-microglobulin Antibody anti-beta2-microglobulin - 2M2,BioLegend,316316

Additional reported applications (for the relevant formats) include: Western blotting, and ELISA.

Host

Mouse

Reactivity

Human

Application

FC -Quality tested

Platform ID

BAB213286982

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-human beta2-microglobulin Antibody anti-beta2-microglobulin - 2M2
Cat. No.316316
HostMouse
RRIDAB_2632828 (BioLegend Cat. No. 316315)AB_2632829 (BioLegend Cat. No. 316316)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number2M2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
Targetbeta2-microglobulin
ImmunogenPurified human β2-microglobulin
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+T cells.

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