PerCP/Cyanine5.5 anti-mouse CD104 Antibody anti-CD104 - 346-11A,BioLegend,123613

Additional reported (for the relevant formats) applications include: immunohistochemical staining1.

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB118543745

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-mouse CD104 Antibody anti-CD104 - 346-11A
Cat. No.123613
HostRat
RRIDAB_2734183 (BioLegend Cat. No. 123613)AB_2734184 (BioLegend Cat. No. 123614)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number346-11A
Concentration0.2 mg/ml
TargetCD104
ImmunogenTumor-associated antigen TSP-180 from BALB/c lung carcinoma
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD104 is a 205 kD type I transmembrane glycoprotein, also known as integrin β4 chain or β4 integrin, that associates with integrin α6 (CD49f) to form the α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells, and a subset of pre-T cells. The CD49f/CD104 heterodimer is an adhesion receptor for laminins (especially laminin 5) and keratin filaments, and is involved in the regulation of hemidesmosome formation and cell proliferation and activation.

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