PerCP/Cyanine5.5 anti-mouse CD104 Antibody anti-CD104 - 346-11A,BioLegend,123614

Additional reported (for the relevant formats) applications include: immunohistochemical staining1.

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB431049992

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePerCP/Cyanine5.5 anti-mouse CD104 Antibody anti-CD104 - 346-11A
Cat. No.123614
HostRat
RRIDAB_2734183 (BioLegend Cat. No. 123613)AB_2734184 (BioLegend Cat. No. 123614)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number346-11A
Concentration0.2 mg/ml
TargetCD104
ImmunogenTumor-associated antigen TSP-180 from BALB/c lung carcinoma
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD104 is a 205 kD type I transmembrane glycoprotein, also known as integrin β4 chain or β4 integrin, that associates with integrin α6 (CD49f) to form the α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on proliferative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells, and a subset of pre-T cells. The CD49f/CD104 heterodimer is an adhesion receptor for laminins (especially laminin 5) and keratin filaments, and is involved in the regulation of hemidesmosome formation and cell proliferation and activation.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.