PerCP/Cyanine5.5 anti-mouse a-GalCer:CD1d complex Antibody a-GalCer:CD1d complex, L363,BioLegend,140514
Additional reported applications (for the relevant formats) include: Surface and intracellular immunofluorescence2and block a-GalCer:mCD1d1 complex induced iNKT activation1.
Host
Mouse
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB869207162
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NamePerCP/Cyanine5.5 anti-mouse a-GalCer:CD1d complex Antibody a-GalCer:CD1d complex, L363
Cat. No.140514
HostMouse
RRIDAB_2783101 (BioLegend Cat. No. 140513)AB_2783102 (BioLegend Cat. No. 140514)
IsotypeMouse IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberL363
Concentration0.2 mg/ml
Immunogenα-GalCer:mCD1d1 complexes coupled to Mycobacterium tuberculosis PPD
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The L363 antibody reacts with α-GalCer:mouse CD1d complex. Glycolipid α-galactosylceramide (α-GalCer) is a potent activator of human and murineiNKT cells and is widely used as a model antigen for the studies ofiNKT-mediated immunity. The glycolipid binds to CD1d and forms a complex which is subsequently recognized byiNKT cells, a subset of T cells expressing invariant TCR α chain Vα14, analogous to the peptide-MHC complex recognition by TCR α/ß T cells.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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