PerCP/Fire™ 780 anti-human FPR1 Antibody, FPR1, W15086B,BioLegend,391611

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB890285775

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePerCP/Fire™ 780 anti-human FPR1 Antibody, FPR1, W15086B
Cat. No.391611
HostMouse
RRIDAB_3683447 (BioLegend Cat. No. 391611)AB_3683447 (BioLegend Cat. No. 391612)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberW15086B
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetFPR1
ImmunogenFull length human FPR1 transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Fire™ 780 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

FPR1 (Formyl Peptide Receptor 1), a G protein-coupled receptor consisting of seven transmembrane domains, is expressed on phagocytic cells and other cell types such as monocytes.  FPR1 is a high affinity receptor forN-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors.  Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release.  Endogenous peptide ligands for this receptor have also been identified.   FPR1 mediates the response to invasion of the host by microbial pathogens and is important in host defense and inflammation.

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