PerCP/Fire™ 806 Anti-human CD45RB Recombinant Antibody, CD45RB, QA20A68,BioLegend,377711

Clone QA20A68 can completely block the binding of MEM-55 to target cells.

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB127816763

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NamePerCP/Fire™ 806 Anti-human CD45RB Recombinant Antibody, CD45RB, QA20A68
Cat. No.377711
HostMouse
RRIDAB_3683412 (BioLegend Cat. No. 377711)AB_3683412 (BioLegend Cat. No. 377712)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberQA20A68
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD45RB
PurityThe antibody was purified by affinity chromatography and conjugated with PerCP/Fire™ 806 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD45RB is a 180-240 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB enhances both T cell receptor and B cell receptor signaling mediated activation. CD45RB negatively regulates protein kinase activity, and negatively regulates cytokine-mediated signaling pathway.

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