Perforin antibody,Genetex,GTX27203

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB369602030

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamePerforin antibody
Cat. No.GTX27203
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenRecombinant full length protein (Rat).
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Perforin (pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte(CTL) (ref 1,2). It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL, which represents an important mechanism in the immune defense against tumors and virus infections (ref 3,4).

Synonyms

Perforin 1 , Cyta , Ratcyta , Prf1

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