Periostin Antibody (YA6145),MedChemexpress,HY-P86453

Periostin Antibody (YA6145) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Periostin.

Host

Rabbit

Reactivity

Human

Application

WB,IHC-P,ICC/IF,IP,ELISA

Conjugate

Non-conjugated

Platform ID

BAB100856378

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Scientific Background

Specifications

NamePeriostin Antibody (YA6145)
Cat. No.HY-P86453
Accession NumberQ15063
Gene ID (Entrez)10631
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,IP,ELISA
Working DilutionsIHC-P: 1:200-1:1000; WB: 1:500-1:2000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200
ClonalityMonoclonal
Clone NumberYA6145
Molecular WeightPredicted band size: 93 kDa; Observed band size: 93 kDa
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Periostin protein, a multifunctional molecule, plays a pivotal role in cellular processes by inducing cell attachment and spreading, demonstrating its significance in cell adhesion dynamics. Moreover, Periostin contributes to the structural integrity of connective tissues by enhancing the incorporation of BMP1 into the fibronectin matrix, leading to the subsequent proteolytic activation of lysyl oxidase LOX. Structurally, Periostin exists as a homodimer, and functionally, it interacts with key partners including BMP1 and fibronectin. This intricate network of interactions underscores the diverse functions of Periostin in mediating cellular adhesion and contributing to the extracellular matrix architecture of connective tissues, highlighting its essential role in maintaining tissue integrity and function.

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