Phospho-H2AX (Ser139) Recombinant Antibody,Bioss,bsm-52163r-TR

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IF

Conjugate

Unconjugated

Platform ID

BAB459667283

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePhospho-H2AX (Ser139) Recombinant Antibody
Cat. No.bsm-52163r-TR
Accession NumberP16104
Gene ID (Entrez)3014
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400 | IHC-F:1:100-500 | IF:
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Jul 2008].

Synonyms

H2A histone family member X; Histone H2A.x; H2afx; H2a.x; H2ax; Hist5-2ax; H2A.X; H2A/X; H2AX; H2AFX; H2AX_HUMAN.

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