Phospho-RPS6(Ser240/Ser244) Antibody (YA5839)(PBS only),MedChemexpress,HY-P86147A

Phospho-RPS6(Ser240/Ser244) Antibody (YA5839) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-RPS6(Ser240/Ser244).

Host

Rabbit

Reactivity

Human,Mouse

Application

WB,IHC-P,ICC/IF

Platform ID

BAB994384980

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NamePhospho-RPS6(Ser240/Ser244) Antibody (YA5839)(PBS only)
Cat. No.HY-P86147A
Accession NumberP62753
Gene ID (Entrez)6194
HostRabbit
IsotypeIgG
ReactivityHuman,Mouse
ApplicationWB,IHC-P,ICC/IF
Working DilutionsWB: 1:1,000; IHC-P: 1:5,000-10,000; ICC/IF: 1:50
ClonalityMonoclonal
Clone NumberYA5839
Molecular WeightPredicted band size: 29 kDa; Observed band size: 33 kDa
ImmunogenSynthetic peptide within Human RPS6 aa 200 to the C-terminus (phospho S240 + S244).
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Ribosomal Protein S6 is a component of the 40S small ribosomal subunit and plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. It is part of the small subunit (SSU) processome, the first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins associate with the nascent pre-rRNA and work together to facilitate RNA folding, modifications, rearrangements, cleavage, and targeted degradation of pre-ribosomal RNA by the RNA exosome.

Synonyms

RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33

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