Phospho-TrkA/B (Tyr490/Tyr516) Antibody (YA139),MedChemexpress,HY-P80862

Phospho-TrkA/B (Tyr490/Tyr516) Antibody (YA139) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-TrkA/B (Tyr490/Tyr516).

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB186137952

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
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MedChemexpress

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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NamePhospho-TrkA/B (Tyr490/Tyr516) Antibody (YA139)
Cat. No.HY-P80862
Accession NumberQ16620
Gene ID (Entrez)4915
HostRabbit
RRIDAB_3102985
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityRecombinant,Monoclonal
Clone NumberYA139
Molecular WeightPredicted band size: 92 kDa; Observed band size: 140 kDa
ImmunogenSynthetic phosphopeptide corresponding to residues surrounding Tyr516 of Human TrkB.The exact sequence is proprietary to MCE.
Purityaffinity purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

TrkA/B: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Synonyms

NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B

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