Phospho-c-Myc (Ser62) Antibody, Rabbit MAb,Sino Biological,68A405-XM01

Rabbit IgG Clone #4609

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB; IHC-P; ICC-IF; FCM; IP

Conjugate

Unconjugated

Platform ID

BAB113209754

Sino Biological

Headquarters

Building 9, Yard 18, Kechuang 10th Street, Beijing Economic-Technological Development Area, Daxing District, Beijing 100176, China

Sino Biological

Contact

Tel: 400-890-9989
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePhospho-c-Myc (Ser62) Antibody, Rabbit MAb
Cat. No.68A405-XM01
HostRabbit
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB; IHC-P; ICC-IF; FCM; IP
Working DilutionsWB:1:500-1:1000; IHC-P:1:200-1:500; ICC-IF:1:500-1:1000; FCM:1:50-1:100; IP:1:20-1:50
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser62 of human c-Myc
Appearance/FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
FormulationLiquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Scientific Background

MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis, and cellular transformation. MYC largely functions as a transcription factor that promotes the expression of numerous target genes to coordinate death, proliferation, and metabolism at the cellular, tissue, and organismal levels. MYC is one of the most important oncogenes in cancer. MYC overexpression can be achieved through a variety of mechanisms, including gene duplications, chromosomal translocations, or somatic mutations leading to increased MYC stability. It is widely expressed in the gall bladder, esophagus, and other tissues. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement.

Synonyms

v-myc avian myelocytomatosis viral oncogene homolog

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.