Placental Alkaline Phosphatase antibody [3E5],Genetex,GTX82823

Host

Mouse

Reactivity

Human

Application

WB IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB628300324

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NamePlacental Alkaline Phosphatase antibody [3E5]
Cat. No.GTX82823
Gene ID (Entrez)250
HostMouse
IsotypeIgG2b
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P ELISA
ClonalityMonoclonal
TargetALPP
ImmunogenPurified recombinant fragment of human ALPP expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]

Synonyms

alkaline phosphatase, placental , ALP , ALPI , IAP , PALP , PLAP , PLAP-1

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