Poly ADP-Ribose Polymerase 1 (PARP1) Antibody,Abbexa,abx239938
Poly ADP-Ribose Polymerase 1 (PARP1) Antibody is a Mouse Monoclonal antibody for the detection of PARP1. PARP1 (poly (ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly (ADP-ribosyl) ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC, IF/ICC
Conjugate
Unconjugated
Platform ID
BAB891288053
Abbexa
Contact
Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951
Email:
Product Specifications
Specifications
NamePoly ADP-Ribose Polymerase 1 (PARP1) Antibody
Cat. No.abx239938
Accession NumberP09874
Gene ID (Entrez)142
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationELISA, WB, IHC, IF/ICC
Working DilutionsWB: 1/5000 - 1/30000, IHC: 1/100 - 1/1000, IF/ICC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
Concentration2 mg/ml
Molecular WeightObserved MW: 115 kDa, 89 kDa
TargetPARP1
Immunogenpoly (ADP-ribose) polymerase 1
PurityPurified by Protein A and Protein G affinity chromatography.
Appearance/FormLiquid
Formulation0.01 M PBS, pH 7.4.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Monoclonal Antibodies
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