Procollagen Lysine-1,2-Oxoglutarate-5-Dioxygenase 1 (PLOD1) Antibody,Abbexa,abx026944

Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity.

Host

Rabbit

Reactivity

Human

Application

ELISA, WB, IHC, FCM

Conjugate

Unconjugated

Platform ID

BAB699646292

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameProcollagen Lysine-1,2-Oxoglutarate-5-Dioxygenase 1 (PLOD1) Antibody
Cat. No.abx026944
Accession NumberQ02809
Gene ID (Entrez)5351
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB, IHC, FCM
Working DilutionsWB: 1/2000, IHC-P: 1/10 - 1/50, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 83.6 kDa
TargetPLOD1
ImmunogenKLH-conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human PLOD1.
PurityPurified through a protein A column, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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