Prolactin Receptor antibody [6G8],Genetex,GTX52971

Host

Mouse

Reactivity

Human

Application

WB Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB186344978

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameProlactin Receptor antibody [6G8]
Cat. No.GTX52971
Gene ID (Entrez)5618
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB Neutralizing /Inhibition
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetPRLR
ImmunogenHuman recombinant Prolactin R EC domain
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

Synonyms

HPRL , MFAB , PRLR , hPRLrI , prolactin receptor , Prolactin Receptor

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