Proliferating Cell Nuclear Antigen (PCNA) Antibody,Abbexa,abx015957
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Two transcript variants encoding the same protein have been found for this gene.Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Host
Mouse
Reactivity
Human, Monkey
Application
ELISA, WB, IHC, FCM
Conjugate
Unconjugated
Platform ID
BAB834104250
Abbexa
Contact
Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951
Email:
Product Specifications
Specifications
NameProliferating Cell Nuclear Antigen (PCNA) Antibody
Cat. No.abx015957
Gene ID (Entrez)5111
HostMouse
IsotypeIgG1
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationELISA, WB, IHC, FCM
Working DilutionsELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConcentrationNot determined.
Molecular Weight28.7 kDa
ImmunogenPurified recombinant fragment of human PCNA (AA: 53-196) expressed in E. coli.
PurityUnpurified ascites.
Appearance/FormLiquid
FormulationAscitic fluid containing 0.03% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Monoclonal Antibodies
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