Pumilio 1 Recombinant Antibody,Bioss,bsm-61918r

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB310904930

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamePumilio 1 Recombinant Antibody
Cat. No.bsm-61918r
Accession NumberQ14671
Gene ID (Entrez)9698
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF
Working DilutionsWB:1:300-5000 | IHC-P:FCM1:20-100 | IHC-F:IHC-P1:200-400 | IP:IHC-F1:100-500 | IF:ICC1:50-200 | Flow-Cyt:IP1-2ug | ICC/IF:IF
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE).Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation.

Synonyms

HsPUM; PUM L1; Pum1; PUMH 1; PUMH; PUMH1; Pumilio1; PUML1.

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