Purified anti-Aldose Reductase AKR1B1 Antibody, Aldose Reductase, 4G9-B6-F6,BioLegend,870302

Host

Mouse

Reactivity

Human, Mouse

Application

WB -Quality testedIHC-P -Verified

Platform ID

BAB811834714

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-Aldose Reductase AKR1B1 Antibody, Aldose Reductase, 4G9-B6-F6
Cat. No.870302
HostMouse
RRIDAB_2820190 (BioLegend Cat. No. 870301)AB_2820191 (BioLegend Cat. No. 870302)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse
ApplicationWB -Quality testedIHC-P -Verified
ClonalityMonoclonal
Clone Number4G9-B6-F6
Concentration0.5 mg/mL
TargetAldose Reductase
ImmunogenPurified recombinant human AKR1B1 protein.
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Aldo-keto reductase 1 member B1 (AKR1B1) is a member of AKR superfamily and catalyzes the NADPH-dependent reduction of a wide range of carbonyl-containing compounds to their corresponding metabolites. It also plays an important role in glucose metabolism. Elevated expression levels of AKR1B1 correlate with breast cancer, neuroinflammation, and astrocyte proliferation via modulating energy metabolism.

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