Purified anti-CAV1 (Caveolin-1) Antibody, CAV1, W23150D,BioLegend,648851

Host

Rat

Reactivity

Human

Application

WB - Quality testedICC, ICFC - Verified

Platform ID

BAB288173548

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NamePurified anti-CAV1 (Caveolin-1) Antibody, CAV1, W23150D
Cat. No.648851
HostRat
RRIDAB_3720576 (BioLegend Cat. No. 648850)AB_3720576 (BioLegend Cat. No. 648851)
IsotypeRat IgG2a, λ
ReactivityHuman
ApplicationWB - Quality testedICC, ICFC - Verified
ClonalityMonoclonal
Clone NumberW23150D
Concentration0.5 mg/mL
TargetCAV1
ImmunogenRecombinant protein corresponding to the C terminus of human Caveolin-1
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Caveolin-1 (CAV1) is a critical structural protein present in caveolae, small invaginations found in the plasma membrane of many cell types. Caveolin-1 helps in the formation and stability of caveolae, acting as a scaffolding protein. It plays a key role in organizing and regulating signaling molecules, influencing various cellular processes such as endocytosis, cholesterol homeostasis, and signal transduction. Additionally, it is involved in modulating cell proliferation, apoptosis, and mechanotransduction. Dysregulation of Caveolin-1 has been linked to several diseases including cancer, cardiovascular disorders, and fibrosis.

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