Purified anti-CD29 Integrin beta1 Antibody anti-CD29 - P5D2,BioLegend,921304
Clone P5D2 interferes with binding of integrin-bearing cells to fibronectin, laminin and collagen but not vitronectin coated surfaces.P5D2 reacts with the integrin β1 subunit and inhibits the function of all β1 integrins.
Host
Mouse
Reactivity
Human
Application
FC - Quality testedBlock - Reported in the literature, not verified in house
Platform ID
BAB327465943

BioLegend
Contact
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Specifications
Scientific Background
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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