Purified anti-CD4 Antibody, CD4, W23082E,BioLegend,649551
For use in immunohistochemistry on formalin-fixed paraffin-embedded tissue (IHC-P), it is recommended to perform antigen retrieval using Citrate Buffer, 10X (Cat. No. 420902) or Tris-EDTA pH 9.0 Antigen Retrieval Buffer (10X) (Cat. No. 422704). Staining intensity may be stronger using Citrate Buffer.This product is not recommended for use in immunocytochemistry (ICC) or intracellular flow cytometry (ICFC).This product does not react with mouse CD4 in Western Blot (WB) or immunohistochemistry on frozen tissues (IHC-F).
Host
Rat
Reactivity
Human
Application
IHC-P - Quality testedWB - Verified
Platform ID
BAB274868673
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePurified anti-CD4 Antibody, CD4, W23082E
Cat. No.649551
HostRat
RRIDAB_3675180 (BioLegend Cat. No. 649551)AB_3675180 (BioLegend Cat. No. 649552)
IsotypeRat IgG2b, κ
ReactivityHuman
ApplicationIHC-P - Quality testedWB - Verified
ClonalityMonoclonal
Clone NumberW23082E
Concentration0.5 mg/mL
TargetCD4
ImmunogenRecombinant fragment of the extracellular domain of human CD4
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
CD4 is a single-chain type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR (T-Cell Receptor)/CD3 complex and binds to the β2 domain of the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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