Purified anti-CDK1 Antibody, CDK1, A20004C,BioLegend,602351

This product was tested and did not produce a detectable signal for mouse cross-reactivity in WB.This product was tested and did not produce a detectable signal for Immunoprecipitation.This product was tested and did not produce a detectable signal in IHC in human skin tissue.

Host

Mouse

Reactivity

Human

Application

WB - Quality testedICC, IP, IHC-P - Verified

Platform ID

BAB239785521

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NamePurified anti-CDK1 Antibody, CDK1, A20004C
Cat. No.602351
HostMouse
RRIDAB_2922631 (BioLegend Cat. No. 602351)AB_2922631 (BioLegend Cat. No. 602352)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationWB - Quality testedICC, IP, IHC-P - Verified
ClonalityMonoclonal
Clone NumberA20004C
Concentration0.5 mg/mL
TargetCDK1
ImmunogenSynthetic peptide of human CDK1
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only

Scientific Background

Cyclin-dependent kinase 1 (CDK1) is a serine/threonine kinase that is ubiquitously expressed in eukaryotes. CDK1 is a catalytic subunit of a protein kinase called the M-phase promoting factor that universally induces entry into mitosis in eukaryotes. CDK1 has been shown to interact with numerous proteins including cyclin A1, cyclin A2, cyclin B1, cyclin B2, BRCA1, dynamin 2, Fyn, Lyn, and p53. In addition to regulation by protein-protein interactions, CDK1 is controlled by phosphorylation, particularly at conserved tyrosine residues. In humans, CDK1 is encoded by the gene CDC2 (cell division control protein homolog 2).

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