Purified anti-DEPTOR Antibody, DEPTOR, W17128A,BioLegend,610202
Host
Rat
Reactivity
Human, Mouse, Rat, Hamster
Application
WB -Quality tested
Platform ID
BAB392634647
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePurified anti-DEPTOR Antibody, DEPTOR, W17128A
Cat. No.610202
HostRat
RRIDAB_2783359 (BioLegend Cat. No. 610201)AB_2783360 (BioLegend Cat. No. 610202)
IsotypeRat IgG2b, κ
ReactivityHuman, Mouse, Rat, Hamster
ApplicationWB -Quality tested
ClonalityMonoclonal
Clone NumberW17128A
Concentration0.5 mg/ml
TargetDEPTOR
ImmunogenRecombinant Human DEPTOR Protein (1-219 a.a.)
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
DEPTOR/DEPDC6, found only in vertebrates, plays an important role in multiple cellular processes such as cell growth, autophagy, apoptosis, ER stress and adipogenesis. It inbibits mTORC1 and mTORC2 kinase activity through direct interaction with mTOR in these complexes. DEPTOR also associates with chromatin and may regulate transcription, and can act as either an oncogene or oncosuppressor depending on cell- or tissue-specific context.
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