Purified anti-DNER,BioLegend,654651
Host
Rat
Reactivity
Human
Application
IHC-P - Quality tested
Platform ID
BAB275068577
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NamePurified anti-DNER
Cat. No.654651
HostRat
RRIDAB_3699080 (BioLegend Cat. No. 654651)AB_3699080 (BioLegend Cat. No. 654652)
IsotypeRat IgG2b, κ
ReactivityHuman
ApplicationIHC-P - Quality tested
ClonalityMonoclonal
Clone NumberW23166E
Concentration0.5 mg/mL
TargetDNER
ImmunogenRecombinant protein corresponding to the N terminus of human DNER
PurityThe antibody was purified by affinity chromatography.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.
Regulatory StatusResearch Use Only
Scientific Background
DNER is a type I transmembrane protein primarily expressed in the nervous system. First identified as a non-canonical Notch ligand, DNER plays a crucial role in neuronal differentiation. DNER is particularly involved in neuron-glial interactions, and abnormalities in DNER function have been associated with neurological disorders and impaired brain development. DNER is expressed in many tissue types and plays a role in a variety of diseases such as COPD, periodontitis, and breast cancer.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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