Purified anti-Doublecortin DCX Antibody, Doublecortin, O94A3,BioLegend,868502

Doublecortin (DCX) is a microtubule-associated protein that is predominantly expressed in embryonic brains by neuronal precursor cells or immature neurons. DCX is also expressed in the adult brains in regions such as subventricular zones and dentate gyrus, where neuronal precursor cells are localized, and thus has been widely used as a marker for neurogenesis. Doublecortin binds to the microtubule cytoskeleton and stabilizes microtubule bundles. Mutation in DCX has been identified in diseases such as X-linked lissencephaly and double cortex syndrome.